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Bromo-DragonFLY Садржај Farmakologija Reference Literatura Vidi još Spoljašnje veze Мени за навигацију502759-67-3Interactive imageInteractive image80147768719838867208998390571054444710496688verifikuj„Bromo-DragonFLY”оригинала„PubChem as a public resource for drug discovery.”2097051910.1016/j.drudis.2010.10.003уреди10.1016/S1574-1400(08)00012-1„Erowid Bromo-DragonFly Vault : Dosage”„Svensk författningssamling (SFS) - Riksdagen”985708410.1021/jm9803525'A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor'10.1021/jm000491yErowid Bromo-Dragonfly vaultBromo-dragonfly – livsfarlig missbruksdrogMan sentenced in 2011 designer drug deaths of two Oklahoma college studentsу

Психоделични фенетиламиниЕнтеогениАгонисти серотонинског рецептораБензодифураниБромоарениДизајниране дроге


psihodelični lekfenetilaminskomLSDμgFinskojŠvedskojNorveškojDanskojstereocentarstereoizomeragonistnim5-HT2Aserotoninski receptorafinitetserotoninskereceptora










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Bromo-DragonFLY




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Bromo-DragonFLY

Kekulé, skeletal formula of bromo-DragonFLY (R)
Nazivi

IUPAC naziv
1-(4-Bromofuro[2,3-f][1]benzofuran-8-il)propan-2-amin[1]

Drugi nazivi
Bromo-benzodifuranil-izopropilamin

Identifikacija

CAS broj



  • 502759-67-3 ДаY


3D model (Jmol)


  • Interactive image

  • Interactive image



ChemSpider


  • 8014776 ДаY


  • 8719838 R ДаY


  • 8672089 S ДаY




PubChem[2][3]CID


  • 9839057


  • 10544447 R


  • 10496688 S





Svojstva

Hemijska formula


C
13NH
12O
2Br

Molarna masa
294,144 g mol−1

log P
2,519

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).


ДаY verifikuj (šta je ДаYНеН ?)

Reference infokutije


Bromo-DragonFLY je psihodelični lek koji je srodan sa fenetilaminskom familijom. Bromo-DragonFLY se smatra ekstremno potentnim halucinogenom, skoro je potenta kao LSD. Njegova normal doza je u opsegu 200 μg do 800 μg. On ima veoma dugo vreme trajanja, i do nekoliko dana.[4] On je nedozvoljena supstanca u Finskoj, Švedskoj,[5]Norveškoj i Danskoj. Bromo-DragonFLY sadrži stereocentar i R-(-)-bromo-DragonFLY je aktivniji stereoizomer.




Садржај





  • 1 Farmakologija


  • 2 Reference


  • 3 Literatura


  • 4 Vidi još


  • 5 Spoljašnje veze




Farmakologija


Halucinogeno dejstvo bromo-DragonFLY je posredovan njegovom agonistnim dejstvom na 5-HT2A serotoninski receptor. Bromo-DragonFLY isto tako ima visok afinitet vezivanja za 5-HT2B i 5-HT2Cserotoninske receptora, te je neselektivni 5-HT2 agonist.[6][7]



Reference




  1. ^ „Bromo-DragonFLY”. Forendex. USA: Southern Association of Forensic Scientists. Архивирано из оригинала на датум 06. 10. 2014. Приступљено 16. 3. 2012. 


  2. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди


  3. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 


  4. ^ „Erowid Bromo-DragonFly Vault : Dosage”. 


  5. ^ „Svensk författningssamling (SFS) - Riksdagen”. 


  6. ^ Parker MA, Marona-Lewicka D, Lucaites VL, Nelson DL, Nichols DE (1998). „A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor”. Journal of Medicinal Chemistry. 41 (26): 5148—9. PMID 9857084. doi:10.1021/jm9803525. 


  7. ^ Corazza O, Schifano F, Farre M, Deluca P, Davey Z, Torrens M, Demetrovics Z, Di Furia L, Flesland L, Siemann H, Skutle A, Van Der Kreeft P, Scherbaum N. Designer drugs on the internet: a phenomenon out-of-control? the emergence of hallucinogenic drug Bromo-Dragonfly. Current Clinical Pharmacology. 2011 May;6(2):125-9. PMID 21592070



Literatura


.mw-parser-output .refbeginfont-size:90%;margin-bottom:0.5em.mw-parser-output .refbegin-hanging-indents>ullist-style-type:none;margin-left:0.mw-parser-output .refbegin-hanging-indents>ul>li,.mw-parser-output .refbegin-hanging-indents>dl>ddmargin-left:0;padding-left:3.2em;text-indent:-3.2em;list-style:none.mw-parser-output .refbegin-100font-size:100%


  • 'A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor' J. Med. Chem. 41(26): 5148-5149

  • 'Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT2A/2C receptor agonists' by J. J. Chambers, D. M. Kurrasch-Orbaugh, M. A. Parker, and D. E. Nichols in J. Med. Chem. 44(6): 1003-1010 (2001) doi:10.1021/jm000491y



Vidi još




  • 2C-B

  • DOB

  • 2C-B-FLY

  • 5-HT2A receptor

  • PiHKAL



Spoljašnje veze



  • Erowid Bromo-Dragonfly vault

  • Bromo-dragonfly – livsfarlig missbruksdrog

  • Man sentenced in 2011 designer drug deaths of two Oklahoma college students








Преузето из „https://sr.wikipedia.org/w/index.php?title=Bromo-DragonFLY&oldid=20743367”










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