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Бромо-ДрагонФЛY Садржај Фармакологија Референце Literatura Види још Спољашње везе Мени за навигацију502759-67-3Интерацтиве имагеИнтерацтиве имаге80147768719838867208998390571054444710496688верификуј„Бромо-ДрагонФЛY”оригинала„PubChem as a public resource for drug discovery.”2097051910.1016/j.drudis.2010.10.003уреди10.1016/S1574-1400(08)00012-1„Erowid Bromo-DragonFly Vault : Dosage”„Svensk författningssamling (SFS) - Riksdagen”985708410.1021/jm9803525'A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor'10.1021/jm000491yErowid Bromo-Dragonfly vaultBromo-dragonfly – livsfarlig missbruksdrogMan sentenced in 2011 designer drug deaths of two Oklahoma college studentsу

Multi tool use
Multi tool use

Психоделични фенетиламиниЕнтеогениАгонисти серотонинског рецептораБензодифураниБромоарениДизајниране дроге


психоделични лекфенетиламинскомЛСДμгФинскојШведскојНорвешкојДанскојстереоцентарстереоизомерагонистним5-HT2Aсеротонински рецепторафинитетсеротонинскерецептора










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Бромо-ДрагонФЛY




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Бромо-ДрагонФЛY

Кекулé, скелетал формула оф бромо-ДрагонФЛY (Р)
Називи

ИУПАЦ назив
1-(4-Бромофуро[2,3-f][1]бензофуран-8-ил)пропан-2-амин[1]

Други називи
Бромо-бензодифуранил-изопропиламин

Идентификација

CAS број



  • 502759-67-3 ДаY


3Д модел (Јмол)


  • Интерацтиве имаге

  • Интерацтиве имаге



ChemSpider


  • 8014776 ДаY


  • 8719838 Р ДаY


  • 8672089 С ДаY




PubChem[2][3]ЦИД


  • 9839057


  • 10544447 Р


  • 10496688 С





Својства

Хемијска формула


C
13НХ
12О
2Бр

Моларна маса
294,144 g mol−1

log P
2,519

Уколико није другачије напоменуто, подаци се односе на стандардно стање материјала (на 25 °Ц [77 °Ф], 100 кПа).


ДаY верификуј (шта је ДаYНеН ?)

Референце инфокутије


Bromo-DragonFLY је психоделични лек који је сродан са фенетиламинском фамилијом. Bromo-DragonFLY се сматра екстремно потентним халуциногеном, скоро је потента као ЛСД. Његова нормал доза је у опсегу 200 μг до 800 μg. Он има веома дуго време трајања, и до неколико дана.[4] Он је недозвољена супстанца у Финској, Шведској,[5]Норвешкој и Данској. Bromo-DragonFLY садржи стереоцентар и R-(-)-bromo-DragonFLY је активнији стереоизомер.




Садржај





  • 1 Фармакологија


  • 2 Референце


  • 3 Литература


  • 4 Види још


  • 5 Спољашње везе




Фармакологија


Халуциногено дејство bromo-DragonFLY је посредован његовом агонистним дејством на 5-HT2A серотонински рецептор. Bromo-DragonFLY исто тако има висок афинитет везивања за 5-HT2B и 5-HT2Cсеротонинске рецептора, те је неселективни 5-HT2 агонист.[6][7]



Референце




  1. ^ „Бромо-ДрагонФЛY”. Форендеx. УСА: Соутхерн Ассоциатион оф Форенсиц Сциентистс. Архивирано из оригинала на датум 06. 10. 2014. Приступљено 16. 3. 2012. 


  2. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди


  3. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 


  4. ^ „Erowid Bromo-DragonFly Vault : Dosage”. 


  5. ^ „Svensk författningssamling (SFS) - Riksdagen”. 


  6. ^ Parker MA, Marona-Lewicka D, Lucaites VL, Nelson DL, Nichols DE (1998). „A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor”. Journal of Medicinal Chemistry. 41 (26): 5148—9. PMID 9857084. doi:10.1021/jm9803525. 


  7. ^ Corazza O, Schifano F, Farre M, Deluca P, Davey Z, Torrens M, Demetrovics Z, Di Furia L, Flesland L, Siemann H, Skutle A, Van Der Kreeft P, Scherbaum N. Designer drugs on the internet: a phenomenon out-of-control? the emergence of hallucinogenic drug Bromo-Dragonfly. Current Clinical Pharmacology. 2011 May;6(2):125-9. PMID 21592070



Literatura


.mw-parser-output .refbeginfont-size:90%;margin-bottom:0.5em.mw-parser-output .refbegin-hanging-indents>ullist-style-type:none;margin-left:0.mw-parser-output .refbegin-hanging-indents>ul>li,.mw-parser-output .refbegin-hanging-indents>dl>ddmargin-left:0;padding-left:3.2em;text-indent:-3.2em;list-style:none.mw-parser-output .refbegin-100font-size:100%


  • 'A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor' J. Med. Chem. 41(26): 5148-5149

  • 'Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT2A/2C receptor agonists' by J. J. Chambers, D. M. Kurrasch-Orbaugh, M. A. Parker, and D. E. Nichols in J. Med. Chem. 44(6): 1003-1010 (2001) doi:10.1021/jm000491y



Види још




  • 2C-B

  • ДОБ

  • 2C-B-FLY

  • 5-HT2A рецептор

  • PiHKAL



Спољашње везе



  • Erowid Bromo-Dragonfly vault

  • Bromo-dragonfly – livsfarlig missbruksdrog

  • Man sentenced in 2011 designer drug deaths of two Oklahoma college students








Преузето из „https://sr.wikipedia.org/w/index.php?title=Bromo-DragonFLY&oldid=20743367”










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Mentenanță CS1: Dată și anMentenanță CS1: Utilizare explicită a lui et al.IsraelȚări în Orientul MijlociuRepubliciSionismState membre ale Organizației Națiunilor Unite ebraicăarabărepublică parlamentarăOrientul MijlociuMării MediteraneLibanulSiriaIordaniaCisiordaniaEgiptFâșia GazaIerusalimTel AvivOrganizației Națiunilor Unite14 mai1948Mandatului britanic pentru PalestinaDavid Ben-GurionOrganizației SionisteAgenției Evreiești pentru PalestinaStatului IsraelONULiga ArabăpalestinieneRăzboiul arabo-israelian din 1948Conflict arabo-israelianTransiordaniaEgiptulRăzboiului de Șase ZileCisiordaniaPeninsula SinaiFâșia GazaÎnălțimile GolanBiroului Central de Statisticădruzicerchezisamariteniarmenidemocrație reprezentativăsistem parlamentarvot universalKnessetulgaze naturaleIndicelui Dezvoltării UmaneOCDEȚara I...
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