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How can a surrogate pass on genes to a fertilized embryo?
How would an immortal hide his/her immortality or maintain it publicly?How can a molecule grant long-life?How might an organism evolve to pass its learned knowledge to its offspring 'genetically'?D&D Campaign - Closing off a Mountain Pass with ExplosivesHow can someone be immortal and still age?How can one manipulate elementary particles to make a person live forever?
.everyoneloves__top-leaderboard:empty,.everyoneloves__mid-leaderboard:empty,.everyoneloves__bot-mid-leaderboard:empty margin-bottom:0;
$begingroup$
I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.
We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.
During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.
How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?
biology magic immortality
$endgroup$
add a comment |
$begingroup$
I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.
We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.
During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.
How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?
biology magic immortality
$endgroup$
$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago
$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago
$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago
$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago
add a comment |
$begingroup$
I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.
We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.
During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.
How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?
biology magic immortality
$endgroup$
I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.
We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.
During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.
How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?
biology magic immortality
biology magic immortality
edited 6 hours ago


Cyn
18.3k2 gold badges36 silver badges83 bronze badges
18.3k2 gold badges36 silver badges83 bronze badges
asked 10 hours ago
IncognitoIncognito
9,8329 gold badges81 silver badges144 bronze badges
9,8329 gold badges81 silver badges144 bronze badges
$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago
$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago
$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago
$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago
add a comment |
$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago
$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago
$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago
$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago
$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago
$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago
$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago
$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago
$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago
$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago
$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago
$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago
add a comment |
2 Answers
2
active
oldest
votes
$begingroup$
You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.
Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.
Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.
New contributor
mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
$endgroup$
add a comment |
$begingroup$
The children are chimeras.
In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.
https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/
The physical connection between mother and fetus is provided by the
placenta, an organ, built of cells from both the mother and fetus,
which serves as a conduit for the exchange of nutrients, gasses, and
wastes. Cells may migrate through the placenta between the mother and
the fetus, taking up residence in many organs of the body including
the lung, thyroid, muscle, liver, heart, kidney and skin. These may
have a broad range of impacts, from tissue repair and cancer
prevention to sparking immune disorders.
It is remarkable that it is so common for cells from one individual to
integrate into the tissues of another distinct person. We are
accustomed to thinking of ourselves as singular autonomous
individuals, and these foreign cells seem to belie that notion, and
suggest that most people carry remnants of other individuals...
It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.
This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.
$endgroup$
add a comment |
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2 Answers
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active
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2 Answers
2
active
oldest
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$begingroup$
You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.
Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.
Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.
New contributor
mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
$endgroup$
add a comment |
$begingroup$
You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.
Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.
Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.
New contributor
mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
$endgroup$
add a comment |
$begingroup$
You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.
Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.
Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.
New contributor
mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
$endgroup$
You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.
Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.
Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.
New contributor
mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
New contributor
mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
answered 8 hours ago


mu 無mu 無
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mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.
add a comment |
add a comment |
$begingroup$
The children are chimeras.
In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.
https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/
The physical connection between mother and fetus is provided by the
placenta, an organ, built of cells from both the mother and fetus,
which serves as a conduit for the exchange of nutrients, gasses, and
wastes. Cells may migrate through the placenta between the mother and
the fetus, taking up residence in many organs of the body including
the lung, thyroid, muscle, liver, heart, kidney and skin. These may
have a broad range of impacts, from tissue repair and cancer
prevention to sparking immune disorders.
It is remarkable that it is so common for cells from one individual to
integrate into the tissues of another distinct person. We are
accustomed to thinking of ourselves as singular autonomous
individuals, and these foreign cells seem to belie that notion, and
suggest that most people carry remnants of other individuals...
It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.
This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.
$endgroup$
add a comment |
$begingroup$
The children are chimeras.
In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.
https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/
The physical connection between mother and fetus is provided by the
placenta, an organ, built of cells from both the mother and fetus,
which serves as a conduit for the exchange of nutrients, gasses, and
wastes. Cells may migrate through the placenta between the mother and
the fetus, taking up residence in many organs of the body including
the lung, thyroid, muscle, liver, heart, kidney and skin. These may
have a broad range of impacts, from tissue repair and cancer
prevention to sparking immune disorders.
It is remarkable that it is so common for cells from one individual to
integrate into the tissues of another distinct person. We are
accustomed to thinking of ourselves as singular autonomous
individuals, and these foreign cells seem to belie that notion, and
suggest that most people carry remnants of other individuals...
It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.
This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.
$endgroup$
add a comment |
$begingroup$
The children are chimeras.
In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.
https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/
The physical connection between mother and fetus is provided by the
placenta, an organ, built of cells from both the mother and fetus,
which serves as a conduit for the exchange of nutrients, gasses, and
wastes. Cells may migrate through the placenta between the mother and
the fetus, taking up residence in many organs of the body including
the lung, thyroid, muscle, liver, heart, kidney and skin. These may
have a broad range of impacts, from tissue repair and cancer
prevention to sparking immune disorders.
It is remarkable that it is so common for cells from one individual to
integrate into the tissues of another distinct person. We are
accustomed to thinking of ourselves as singular autonomous
individuals, and these foreign cells seem to belie that notion, and
suggest that most people carry remnants of other individuals...
It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.
This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.
$endgroup$
The children are chimeras.
In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.
https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/
The physical connection between mother and fetus is provided by the
placenta, an organ, built of cells from both the mother and fetus,
which serves as a conduit for the exchange of nutrients, gasses, and
wastes. Cells may migrate through the placenta between the mother and
the fetus, taking up residence in many organs of the body including
the lung, thyroid, muscle, liver, heart, kidney and skin. These may
have a broad range of impacts, from tissue repair and cancer
prevention to sparking immune disorders.
It is remarkable that it is so common for cells from one individual to
integrate into the tissues of another distinct person. We are
accustomed to thinking of ourselves as singular autonomous
individuals, and these foreign cells seem to belie that notion, and
suggest that most people carry remnants of other individuals...
It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.
This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.
answered 7 hours ago


WillkWillk
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You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
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– user535733
9 hours ago
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@user535733 what's wrong with surrogate? Isn't that what it is?
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– Incognito
9 hours ago
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In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
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– user535733
9 hours ago
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I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
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– Cyn
6 hours ago