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How can a surrogate pass on genes to a fertilized embryo?


How would an immortal hide his/her immortality or maintain it publicly?How can a molecule grant long-life?How might an organism evolve to pass its learned knowledge to its offspring 'genetically'?D&D Campaign - Closing off a Mountain Pass with ExplosivesHow can someone be immortal and still age?How can one manipulate elementary particles to make a person live forever?






.everyoneloves__top-leaderboard:empty,.everyoneloves__mid-leaderboard:empty,.everyoneloves__bot-mid-leaderboard:empty margin-bottom:0;








4












$begingroup$


I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.



We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.



During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.



How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?










share|improve this question











$endgroup$













  • $begingroup$
    You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
    $endgroup$
    – user535733
    9 hours ago










  • $begingroup$
    @user535733 what's wrong with surrogate? Isn't that what it is?
    $endgroup$
    – Incognito
    9 hours ago










  • $begingroup$
    In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
    $endgroup$
    – user535733
    9 hours ago











  • $begingroup$
    I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
    $endgroup$
    – Cyn
    6 hours ago

















4












$begingroup$


I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.



We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.



During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.



How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?










share|improve this question











$endgroup$













  • $begingroup$
    You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
    $endgroup$
    – user535733
    9 hours ago










  • $begingroup$
    @user535733 what's wrong with surrogate? Isn't that what it is?
    $endgroup$
    – Incognito
    9 hours ago










  • $begingroup$
    In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
    $endgroup$
    – user535733
    9 hours ago











  • $begingroup$
    I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
    $endgroup$
    – Cyn
    6 hours ago













4












4








4


1



$begingroup$


I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.



We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.



During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.



How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?










share|improve this question











$endgroup$




I am part of a group of immortals from the planet Ziest. From the dawn of time we came…moving silently down through the centuries. Living many secret lives, struggling to reach the time of the gathering, when the few who remain will battle to the last.



We immortals unfortunately cannot create progeny, as our bodies cannot produce the sex cells necessary to make offspring. However, recent technology have allowed immortals to become surrogates, allowing them to pass on their immortal genes to the next generation. A fertilized egg from two mortals is put into the womb of a female immortal, allowing it to gestate there.



During pregnancy, placenta separates the baby’s and the mother’s DNA. When the baby forms in utero, the placenta forms along with it. The primary purpose of the placenta is to be a gatekeeper. It provides the growing baby with nourishment and sustenance, and is one of the main protectors of the integrity of the fetus. Only specific matter can go through to the baby, meaning that the DNA of the carrier stay on the other side of the placenta. This is meant to protect both parties, as too many cells passing between mother and child can be dangerous to both.



How can this be modified to allow the surrogate to pass on their genes without endangering the lives of the carrier or child?







biology magic immortality






share|improve this question















share|improve this question













share|improve this question




share|improve this question








edited 6 hours ago









Cyn

18.3k2 gold badges36 silver badges83 bronze badges




18.3k2 gold badges36 silver badges83 bronze badges










asked 10 hours ago









IncognitoIncognito

9,8329 gold badges81 silver badges144 bronze badges




9,8329 gold badges81 silver badges144 bronze badges














  • $begingroup$
    You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
    $endgroup$
    – user535733
    9 hours ago










  • $begingroup$
    @user535733 what's wrong with surrogate? Isn't that what it is?
    $endgroup$
    – Incognito
    9 hours ago










  • $begingroup$
    In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
    $endgroup$
    – user535733
    9 hours ago











  • $begingroup$
    I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
    $endgroup$
    – Cyn
    6 hours ago
















  • $begingroup$
    You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
    $endgroup$
    – user535733
    9 hours ago










  • $begingroup$
    @user535733 what's wrong with surrogate? Isn't that what it is?
    $endgroup$
    – Incognito
    9 hours ago










  • $begingroup$
    In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
    $endgroup$
    – user535733
    9 hours ago











  • $begingroup$
    I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
    $endgroup$
    – Cyn
    6 hours ago















$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago




$begingroup$
You might want to call them something other than "surrogate." Aside from the immortal aspect, this seems rather close to Iain Banks' Azadians in The Player Of Games. He called the third gender an 'apex' and handwaved 'an RNA analogue' for the passing of genes.
$endgroup$
– user535733
9 hours ago












$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago




$begingroup$
@user535733 what's wrong with surrogate? Isn't that what it is?
$endgroup$
– Incognito
9 hours ago












$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago





$begingroup$
In one sense, yes. In another sense, no. That's why using the term will confuse some folks. If they contribute genes, then they are a gendered parent, not a mere maturation vessel. See? Gets confusing fast, depending upon the point of view.
$endgroup$
– user535733
9 hours ago













$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago




$begingroup$
I removed science because that's for asking about science the profession/concept in a fictional world and not about making a question scientific. If you want the latter, you might want the tag science-based, but it may not be right for a question about fantasy.
$endgroup$
– Cyn
6 hours ago










2 Answers
2






active

oldest

votes


















4












$begingroup$

You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.



Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.



Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.






share|improve this answer








New contributor



mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.





$endgroup$






















    2












    $begingroup$

    The children are chimeras.



    In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.



    https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/




    The physical connection between mother and fetus is provided by the
    placenta, an organ, built of cells from both the mother and fetus,
    which serves as a conduit for the exchange of nutrients, gasses, and
    wastes. Cells may migrate through the placenta between the mother and
    the fetus, taking up residence in many organs of the body including
    the lung, thyroid, muscle, liver, heart, kidney and skin. These may
    have a broad range of impacts, from tissue repair and cancer
    prevention to sparking immune disorders.



    It is remarkable that it is so common for cells from one individual to
    integrate into the tissues of another distinct person. We are
    accustomed to thinking of ourselves as singular autonomous
    individuals, and these foreign cells seem to belie that notion, and
    suggest that most people carry remnants of other individuals...




    It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.



    This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.






    share|improve this answer









    $endgroup$

















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      2 Answers
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      2 Answers
      2






      active

      oldest

      votes









      active

      oldest

      votes






      active

      oldest

      votes









      4












      $begingroup$

      You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.



      Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.



      Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.






      share|improve this answer








      New contributor



      mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
      Check out our Code of Conduct.





      $endgroup$



















        4












        $begingroup$

        You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.



        Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.



        Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.






        share|improve this answer








        New contributor



        mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.





        $endgroup$

















          4












          4








          4





          $begingroup$

          You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.



          Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.



          Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.






          share|improve this answer








          New contributor



          mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
          Check out our Code of Conduct.





          $endgroup$



          You could change the premise of infertility in the immortals of Zeist from an inability to produce sex cells, to the cells being produced being dud/defective due to an inherited disease of the nuclei.



          Once you establish the above, you can then use the technique of three parent baby (used in real life) to allow for transfer of the nuclei in the reproductive cell, which will ensure that the mitochondrial DNA of the immortals of Zeist gets transferred to the babies.



          Next, you need to establish that the mitochondrial DNA is source for some of the pecular traits of the immortals of Zeist, which can now be inherited with advances of technology.







          share|improve this answer








          New contributor



          mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
          Check out our Code of Conduct.








          share|improve this answer



          share|improve this answer






          New contributor



          mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
          Check out our Code of Conduct.








          answered 8 hours ago









          mu 無mu 無

          1413 bronze badges




          1413 bronze badges




          New contributor



          mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
          Check out our Code of Conduct.




          New contributor




          mu 無 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
          Check out our Code of Conduct.




























              2












              $begingroup$

              The children are chimeras.



              In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.



              https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/




              The physical connection between mother and fetus is provided by the
              placenta, an organ, built of cells from both the mother and fetus,
              which serves as a conduit for the exchange of nutrients, gasses, and
              wastes. Cells may migrate through the placenta between the mother and
              the fetus, taking up residence in many organs of the body including
              the lung, thyroid, muscle, liver, heart, kidney and skin. These may
              have a broad range of impacts, from tissue repair and cancer
              prevention to sparking immune disorders.



              It is remarkable that it is so common for cells from one individual to
              integrate into the tissues of another distinct person. We are
              accustomed to thinking of ourselves as singular autonomous
              individuals, and these foreign cells seem to belie that notion, and
              suggest that most people carry remnants of other individuals...




              It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.



              This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.






              share|improve this answer









              $endgroup$



















                2












                $begingroup$

                The children are chimeras.



                In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.



                https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/




                The physical connection between mother and fetus is provided by the
                placenta, an organ, built of cells from both the mother and fetus,
                which serves as a conduit for the exchange of nutrients, gasses, and
                wastes. Cells may migrate through the placenta between the mother and
                the fetus, taking up residence in many organs of the body including
                the lung, thyroid, muscle, liver, heart, kidney and skin. These may
                have a broad range of impacts, from tissue repair and cancer
                prevention to sparking immune disorders.



                It is remarkable that it is so common for cells from one individual to
                integrate into the tissues of another distinct person. We are
                accustomed to thinking of ourselves as singular autonomous
                individuals, and these foreign cells seem to belie that notion, and
                suggest that most people carry remnants of other individuals...




                It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.



                This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.






                share|improve this answer









                $endgroup$

















                  2












                  2








                  2





                  $begingroup$

                  The children are chimeras.



                  In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.



                  https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/




                  The physical connection between mother and fetus is provided by the
                  placenta, an organ, built of cells from both the mother and fetus,
                  which serves as a conduit for the exchange of nutrients, gasses, and
                  wastes. Cells may migrate through the placenta between the mother and
                  the fetus, taking up residence in many organs of the body including
                  the lung, thyroid, muscle, liver, heart, kidney and skin. These may
                  have a broad range of impacts, from tissue repair and cancer
                  prevention to sparking immune disorders.



                  It is remarkable that it is so common for cells from one individual to
                  integrate into the tissues of another distinct person. We are
                  accustomed to thinking of ourselves as singular autonomous
                  individuals, and these foreign cells seem to belie that notion, and
                  suggest that most people carry remnants of other individuals...




                  It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.



                  This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.






                  share|improve this answer









                  $endgroup$



                  The children are chimeras.



                  In our world, cells from a fetus can move thru the placenta and take up long term residence in the mother.



                  https://www.scientificamerican.com/article/scientists-discover-childrens-cells-living-in-mothers-brain/




                  The physical connection between mother and fetus is provided by the
                  placenta, an organ, built of cells from both the mother and fetus,
                  which serves as a conduit for the exchange of nutrients, gasses, and
                  wastes. Cells may migrate through the placenta between the mother and
                  the fetus, taking up residence in many organs of the body including
                  the lung, thyroid, muscle, liver, heart, kidney and skin. These may
                  have a broad range of impacts, from tissue repair and cancer
                  prevention to sparking immune disorders.



                  It is remarkable that it is so common for cells from one individual to
                  integrate into the tissues of another distinct person. We are
                  accustomed to thinking of ourselves as singular autonomous
                  individuals, and these foreign cells seem to belie that notion, and
                  suggest that most people carry remnants of other individuals...




                  It is easy to detect male cells in a female because you can look for cells with a Y chromosome. There is no reason to doubt that the exchange is reciprocal - mother cells moving in and taking up residence in the fetus.



                  This is how your immortals pass on their genes. Their cells move thru the placenta and take up residence in the growing fetus. Immortal cells in residence then gradually and gently compete for space with the cells of the native human, taking advantage of the scaffolding grown by the fetus and gradually edging out the natives over time. It might take a lot of time but eventually the individual is effectively a clone of the "surrogate", with the mortal cells of the original having died out over the decades.







                  share|improve this answer












                  share|improve this answer



                  share|improve this answer










                  answered 7 hours ago









                  WillkWillk

                  133k34 gold badges253 silver badges558 bronze badges




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