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Blokator kalcijumskih kanala Reference Vidi još Spoljašnje vere Мени за навигацију„calcium channel blocker at Dorland's Medical Dictionary”„Drug treatment of elevated blood pressure”оригинала„Calcium Channel Blockers”„Major side effects and safety of calcium channel blockers”оригиналаCalcium+Channel+BlockersOfficial Adalat (Nifedipine) site, Bayerу

Блокатори калцијумских канала


kalcijumakalcijumove kanaleantihipertenzivni lekovikrvnog pritiskahipertenzijompulsabola u grudimaanginom pektorismigrenaanalgetik












Blokator kalcijumskih kanala




Из Википедије, слободне енциклопедије

(преусмерено са Blokatori kalcijumskih kanala)





Иди на навигацију
Иди на претрагу


Blokatori kalcijumskih kanala (CCB) su hemikalije koje ometaju kretanje kalcijuma (Ca2+) kroz kalcijumove kanale.[1] Blokatori kalcijumskih kanala se koriste kao antihipertenzivni lekovi, i.e. kao lekovi za sniženje krvnog pritiska kod pacijenata sa hipertenzijom. Oni su posebno efektivni protiv krutoće velikih sudova, što je jedan od čestih uzroka povišenog sistolnog krvnog pritiska kod pacijenata u godinama.[2] Blokatori kalcijumskih kanala se često koriste za promenu pulsa, sprečavanje moždanih vazospazama, i redukovanje bola u grudima uzgorkovanog anginom pektoris. Jedan tip blokatora kalcijumovog kanala se eksperimentalno koristi za sprečavanje migrena, dok se jedan drugi izučava kao jak analgetik.


Uprkos njihove efektivenosti, lekovi ove klase imaju visoku stopu mortaliteta pri dugotrajnoj upotrebi, kao i višestruke nuspojave.[3] Potencijalno ozbiljni rizici su prvenstveno vezani za CCB lekove sa kratkotrajnim dejstvom.[4]



Reference




  1. ^ „calcium channel blocker at Dorland's Medical Dictionary”. 


  2. ^ Nelson M (2010). „Drug treatment of elevated blood pressure” (PDF). Australian Prescriber. 33 (4): 108—112. Архивирано из оригинала (pdf) на датум 10. 03. 2012. Приступљено 26. 09. 2013. 


  3. ^ „Calcium Channel Blockers”. MedicineNet. стр. 2. 


  4. ^ Norman M Kaplan, MD; Burton D Rose, MD (3. 4. 2000). „Major side effects and safety of calcium channel blockers”. Chinese Medical & Biological Information. Архивирано из оригинала на датум 30. 12. 2011. Приступљено 26. 09. 2013. 




Vidi još


  • ACE inhibitor

  • Nitrat


Spoljašnje vere



  • MeSH Calcium+Channel+Blockers

  • Official Adalat (Nifedipine) site, Bayer







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