Fluklorolon acetonid Садржај Osobine Reference Literatura Spoljašnje veze Мени за навигацијуacetonide.html Monografija3693-39-8WHO20054914MG258KTA3760900„Long-term treatment with 0-01% fluclorolone acetonide in children”1639042125285510.1136/bmj.1.6010.627„Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”10.1021/jp980230o„Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”1174957310.1021/ci000392t„Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”1102028610.1021/jm000942eGoodman & Gilman's The Pharmacological Basis of Therapeutics10.1036/0071422803Foye's Principles of Medicinal ChemistryFluklorolon acetonidVikimedijinoj ostaviFluclorolone acetonideу
АлкохолиСтероидиКетониОрганофлуоридиОрганохлоридиКетали
INNUSANkortikosteroidorgansko jedinjenjeatomaugljenikamolekulsku masuDaMENDanatphysdevphormcellnocodcongtumrsysieponproclekA10H1H2H3H5
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Fluklorolon acetonid
(преусмерено са Fluklorolon)
Иди на навигацију
Иди на претрагу
 | |
| Klinički podaci | |
|---|---|
| Drugs.com | acetonide.html Monografija |
| Identifikatori | |
| CAS broj | 3693-39-8  Y |
| ATC kod | D07AC02 (WHO) |
| PubChem | CID 20054914 |
| UNII | MG258KTA37 Y |
| Hemijski podaci | |
| Formula | C24H29Cl2FO5 |
| Molarna masa | 487,388 |
SMILES
| |
InChI
| |
Fluklorolon acetonid (INN, ili flukloronid, USAN, s prodajnim imenima Cutanit, Topicon) kortikosteroid je za topikalnu primenu na koži.[1]
Slobodni fluklorolon, bez acetonida (C21H25Cl2FO5, PubChem 60900)
Садржај
1 Osobine
2 Reference
3 Literatura
4 Spoljašnje veze
Osobine
Fluklorolon acetonid je organsko jedinjenje, koje sadrži 24 atoma ugljenika i ima molekulsku masu od 487,388 Da.
| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 5 |
| Broj donora vodonika | 1 |
| Broj rotacionih veza | 2 |
Particioni koeficijent[2] (ALogP) | 2,5 |
Rastvorljivost[3] (logS, log(mol/L)) | -6,7 |
Polarna površina[4] (PSA, Å2) | 72,8 |
Reference
^ Cunliffe, W. J. (1976). „Long-term treatment with 0-01% fluclorolone acetonide in children”. British Medical Journal. 1 (6010): 627. PMC 1639042
. PMID 1252855. doi:10.1136/bmj.1.6010.627.
^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
.mw-parser-output .refbeginfont-size:90%;margin-bottom:0.5em.mw-parser-output .refbegin-hanging-indents>ullist-style-type:none;margin-left:0.mw-parser-output .refbegin-hanging-indents>ul>li,.mw-parser-output .refbegin-hanging-indents>dl>ddmargin-left:0;padding-left:3.2em;text-indent:-3.2em;list-style:none.mw-parser-output .refbegin-100font-size:100%
Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
Spoljašnje veze
 | Fluklorolon acetonid na Vikimedijinoj ostavi. |
- Fluclorolone acetonide
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
Категорије:
- Алкохоли
- Стероиди
- Кетони
- Органофлуориди
- Органохлориди
- Кетали
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