Halometazon Садржај Osobine Reference Literatura Spoljašnje veze Мени за навигацијуMonografija50629-82-8WHO98463328022046J69Z9UU41Z„Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”10.1021/jp980230o„Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”1174957310.1021/ci000392t„Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”1102028610.1021/jm000942eGoodman & Gilman's The Pharmacological Basis of Therapeutics10.1036/0071422803Foye's Principles of Medicinal ChemistryHalometazonVikimedijinoj ostaviHalometasoneу
АлкохолиСтероидиКетониОрганофлуоридиОрганохлориди
organsko jedinjenjeatomaugljenikamolekulsku masuDaMENDanatphysdevphormcellnocodcongtumrsysieponproclekA10H1H2H3H5
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Halometazon
Иди на навигацију
Иди на претрагу
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 | |
| Klinički podaci | |
|---|---|
| Drugs.com | Monografija |
| Identifikatori | |
| CAS broj | 50629-82-8  Y |
| ATC kod | D07AC12 (WHO) |
| PubChem | CID 9846332 |
| ChemSpider | 8022046 Y |
| UNII | J69Z9UU41Z Y |
| Sinonimi | (6S,8S,9R,10S,11S,13S,16R,17R)-2-chloro-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
| Hemijski podaci | |
| Formula | C22H27ClF2O5 |
| Molarna masa | 444,897 |
SMILES
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InChI
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Halometazon je organsko jedinjenje, koje sadrži 22 atoma ugljenika i ima molekulsku masu od 444,897 Da.
Садржај
1 Osobine
2 Reference
3 Literatura
4 Spoljašnje veze
Osobine
| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 5 |
| Broj donora vodonika | 3 |
| Broj rotacionih veza | 2 |
Particioni koeficijent[1] (ALogP) | 1,9 |
Rastvorljivost[2] (logS, log(mol/L)) | -4,9 |
Polarna površina[3] (PSA, Å2) | 94,8 |
Reference
^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
.mw-parser-output .refbeginfont-size:90%;margin-bottom:0.5em.mw-parser-output .refbegin-hanging-indents>ullist-style-type:none;margin-left:0.mw-parser-output .refbegin-hanging-indents>ul>li,.mw-parser-output .refbegin-hanging-indents>dl>ddmargin-left:0;padding-left:3.2em;text-indent:-3.2em;list-style:none.mw-parser-output .refbegin-100font-size:100%
Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
Spoljašnje veze
 | Halometazon na Vikimedijinoj ostavi. |
- Halometasone
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
Категорије:
- Алкохоли
- Стероиди
- Кетони
- Органофлуориди
- Органохлориди
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