CortisoneCortisone acetateCortodoxone (cortexolone, 11-deoxycortisol)Desoxycortone (deoxycortone, cortexone, 11-deoxycorticosterone)Desoxycortone estersHydrocortisonecortisolHydrocortisone estersPrebediolone acetatePregnenolonePregnenolone acetatePregnenolone succinateChloroprednisoneCloprednolDifluprednateFludrocortisoneFlugestone acetate (flurogestone acetate)FluocinoloneFluorometholoneFluorometholone acetateFluperoloneFluperolone acetateFluprednisoloneFluprednisolone estersLoteprednolMedrysoneMethylprednisoloneMethylprednisolone estersPrednicarbatePrednisolonePrednisoneTixocortolTixocortol pivalateAlclometasoneBeclometasoneBeclometasone estersBetamethasoneBetamethasone estersClobetasolClobetasol propionateClobetasoneClocortoloneClocortolone estersCortivazolDesoximetasoneDexamethasoneDexamethasone estersDiflorasoneDiflucortoloneDiflucortolone valerateFlucloroloneFlumetasoneFluocortinFluocortoloneFluocortolone estersFluprednidene acetateFluticasone furoateFluticasone propionateHalometasoneMeprednisoneMometasoneMometasone furoateParamethasonePrednylideneRimexoloneTriamcinoloneUlobetasol (halobetasol)AmcinonideBudesonideCiclesonideDeflazacortDesonideFluclorolone acetonide (flucloronide)Fludroxycortide (flurandrenolone, flurandrenolide)FlunisolideFluocinolone acetonideFluocinonideFormocortal (fluoroformylone)HalcinonideTriamcinolone acetonideTriamcinolone acetonide estersAglepristoneKetoconazoleMifepristoneUlipristal acetateWHO-EMWithdrawnClinical trialsPhase III
DiolsGlucocorticoidsPregnanesTriketonesSystemic hormonal preparation stubs
glucocorticoidmethylatedprednisone
Meprednisone
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Meprednisone
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Clinical data |
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AHFS/Drugs.com
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International Drug Names |
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ATC code |
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Identifiers |
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IUPAC name - (16β)-17,21-dihydroxy-16-methylpregna-1,4-diene-3,11,20-trione
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CAS Number |
1247-42-3 N
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PubChem CID
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ChemSpider |
4447637 Y
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UNII |
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KEGG |
D06673 Y
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ChEMBL |
ChEMBL1201148 N
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CompTox Dashboard (EPA)
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- DTXSID8023260
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ECHA InfoCard |
100.013.633 |
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Chemical and physical data |
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Formula |
C22H28O5 |
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Molar mass |
372.455 g/mol g·mol−1 |
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3D model (JSmol) |
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SMILES O=C(CO)[C@@]3(O)[C@@H](C)C[C@H]2[C@@H]4CCC1=CC(=O)C=C/[C@]1(C)[C@H]4C(=O)C[C@@]23C
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InChI InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,12,15-16,19,23,27H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,19+,20-,21-,22-/m0/s1 Y
Key:PIDANAQULIKBQS-RNUIGHNZSA-N Y
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.mw-parser-output .noboldfont-weight:normal NY (what is this?) (verify)
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Meprednisone is a glucocorticoid. It is a methylated derivative of prednisone.
See also
- Glucocorticoid
- Corticosteroid
References
Glucocorticoids and antiglucocorticoids (H02)
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Glucocorticoids |
Natural |
Cortisone
- Cortodoxone (cortexolone, 11-deoxycortisol)
Desoxycortone (deoxycortone, cortexone, 11-deoxycorticosterone)
Hydrocortisone (cortisol)#
- Prebediolone acetate
Pregnenolone
- Pregnenolone acetate
- Pregnenolone succinate
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Synthetic |
Cortisol-like and related (16-unsubstituted): Chloroprednisone
- Cloprednol
- Difluprednate
- Fludrocortisone
- Flugestone acetate (flurogestone acetate)
- Fluocinolone
Fluorometholone
Fluperolone
Fluprednisolone
- Loteprednol
- Medrysone
Methylprednisolone
- Methylprednisolone esters
- Prednicarbate
Prednisolone#
- Prednisone
Tixocortol
Methasones and related (16-substituted): Alclometasone
Beclometasone
Betamethasone#
Clobetasol
- Clobetasone
Clocortolone
- Cortivazol
- Desoximetasone
Dexamethasone
- Diflorasone
Diflucortolone
- Fluclorolone
- Flumetasone
- Fluocortin
Fluocortolone
- Fluprednidene acetate
- Fluticasone
- Fluticasone furoate
- Fluticasone propionate
- Halometasone
- Meprednisone
Mometasone
- Paramethasone
- Prednylidene
- Rimexolone
- Triamcinolone
- Ulobetasol (halobetasol)
Cyclic ketals (16,17-cyclized): Amcinonide
- Budesonide
- Ciclesonide
- Deflazacort
- Desonide
- Fluclorolone acetonide (flucloronide)
- Fludroxycortide (flurandrenolone, flurandrenolide)
- Flunisolide
- Fluocinolone acetonide
- Fluocinonide
- Formocortal (fluoroformylone)
- Halcinonide
Triamcinolone acetonide
- Triamcinolone acetonide esters
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Antiglucocorticoids |
Antagonists: Aglepristone
- Ketoconazole
- Mifepristone
- Ulipristal acetate
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Synthesis modifiers |
- Acetoxolone
- Aminoglutethimide
- Carbenoxolone
- Enoxolone
- Ketoconazole
- Metyrapone
- Mitotane
- Trilostane
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#WHO-EM
‡Withdrawn from market
Clinical trials:
†Phase III
§Never to phase III
- See also
- Glucocorticoid receptor modulators
- Mineralocorticoids and antimineralocorticoids
- List of corticosteroids
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Glucocorticoid receptor modulators
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GR |
Agonists |
Cortisol-like and related (16-unsubstituted): 3α,5α-Tetrahydrocorticosterone
- 5α-Dihydrocorticosterone
- 9α-Fluorocortisone (alfluorone)
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
- 11-Dehydrocorticosterone acetate
11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)
11-Deoxycortisol (cortodoxone, cortexolone)
- Cortifen (cortiphen, kortifen)
- Cortodoxone acetate
- 21-Deoxycortisol
Δ7-Prednisolone
- Δ7-Prednisolone 21-acetate
- Amebucort
Chloroprednisone
Cloprednol
Corticosterone
- Corticosterone acetate
- Corticosterone benzoate
Cortisol (hydrocortisone)
- Benzodrocortisone (hydrocortisone benzoate)
- Hydrocortamate (hydrocortisone diethylaminoacetate)
- Hydrocortisone esters
Cortisone
Deprodone
Dichlorisone
- Dichlorisone acetate
- Dichlorisone diacetate
- Difluprednate
- Endrisone (endrysone)
Etiprednol
- Etiprednol dicloacetate (etiprednol dichloroacetate)
Fludrocortisone (fludrocortone)
Fluorometholone
Fluperolone
Fluprednisolone
Halopredone
- Halopredone acetate (halopredone diacetate)
Isoflupredone (9α-fluoroprednisolone)
Loteprednol
- Mazipredone (depersolone)
- Medrysone
Methylprednisolone
- Methylprednisolone esters
Prebediolone
Prednisolone
- Prednazate
- Prednazoline
- Prednicarbate (prednisolone ethylcarbonate propionate)
- Prednimustine
- Prednisolamate (prednisolone diethylaminoacetate)
- Prednisolone esters
Prednisone
Pregnenolone
- Pregnenolone acetate
- Pregnenolone succinate (pregnenolone hemisuccinate)
- Resocortol
- Tipredane
Tixocortol
Butixocort (tixocortol butyrate)
- Tixocortol pivalate
Methasones and related (16-substituted): 16α-Methyl-11-oxoprednisolone
Alclometasone
- Alclometasone dipropionate
- Amelometasone
Beclometasone (beclomethasone)
Betamethasone (betametasone)
- Betamethasone esters
- Cortobenzolone (betamethasone salicylate)
- Ciclometasone (ciclomethasone, cyclomethasone)
Clobetasol
Clobetasone
Clocortolone
Cloticasone
Cormetasone (cormethasone)
- Descinolone
- Desoximetasone (desoxymethasone)
Dexamethasone (dexametasone)
Diflorasone
Diflucortolone
- Diflucortolone pivalate
- Diflucortolone valerate
Dimesone
- Doxibetasol (doxybetasol)
- Fluclorolone
Flumetasone (flumethasone)
- Flumetasone acetate
- Flumetasone pivalate
- Fluocinolone
Fluocortin
- Fluocortin butyl (fluocortin butylate)
Fluocortolone
Fluprednidene (fluprednylidene)
- Fluticasone
- Fluticasone furoate
- Fluticasone propionate
- Halocortolone
- Halometasone
Icometasone
- Icometasone enbutate (icometasone butyrate acetate)
- Isoprednidene
Locicortolone (locicortone)
- Locicortolone dicibate (locicortone dicibate)
Meclorisone
Meprednisone (methylprednisone)
- Meprednisone acetate
- Meprednisone hydrogen succinate (methylprednisone hemisuccinate)
Mometasone
Paramethasone
- Paramethasone acetate
- Paramethasone disodium phosphate
- Paramethasone phosphate
Prednylidene
- Prednylidene diethylaminoacetate
- Rimexolone
Ticabesone
Timobesone
Triamcinolone
Ulobetasol (halobetasol)
- Vamorolone
Cyclic ketals (16,17-cyclized): Acrocinonide (triamcinolone acroleinide)
- Amcinafal (triamcinolone pentanonide)
- Amcinafide (triamcinolone acetophenide)
- Amcinonide (triamcinolone acetate cyclopentanonide)
- Budesonide
- Ciclesonide
- Cicortonide
- Deflazacort (azacort)
- Descinolone acetonide
Desonide (hydroxyprednisolone acetonide)
- Desonide disodium phosphate
- Desonide pivalate
- Dexbudesonide
Drocinonide
- Fluazacort
- Fluclorolone acetonide (flucloronide)
- Fludroxycortide (flurandrenolone, flurandrenolide)
- Flumoxonide
Flunisolide
Fluocinolone acetonide
- Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate)
- Fluocinonide (fluocinolide, fluocinolone acetonide acetate)
- Procinonide (fluocinolone acetonide propionate)
- Formocortal
- Halcinonide
- Itrocinonide
Rofleponide
- Tralonide
Triamcinolone acetonide
- Flupamesone (triamcinolone acetonide metembonate)
- Triamcinolone acetonide esters
- Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)
- Triclonide
Others/atypical (other expanded steroid ring systems, homosteroids, and non-pregnane steroids): Cortisuzol
- Cortivazol
- Domoprednate
- Naflocort
Nicocortonide
- Nivacortol (nivazol)
- Oxisopred
- RU-26988
- RU-28362
Non-corticosteroids with some glucocorticoid activity: 15β-Hydroxycyproterone acetate
- 17α-Hydroxyprogesterone
- Bromoketoprogesterone
- Chlormadinone acetate
- Cyproterone
- Cyproterone acetate
- Danazol
- Delmadinone acetate
- Desogestrel
- DU-41165
- Etonogestrel
- Flugestone
- Flugestone acetate (flurogestone acetate)
- Fluoromedroxyprogesterone acetate
- Fluoxymesterone
- Gestodene
- Medrogestone
- Medroxyprogesterone acetate
- Megestrol acetate
- Metribolone
- Norgestomet
- Osaterone acetate
- Progesterone
- Promegestone
- RU-2309
- Quingestrone
- Segesterone acetate (nestorone)
- Tetrahydrogestrinone
Nonsteroidal glucocorticoids: AZD-5423
- GSK-9027
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Mixed (SEGRMs) |
- Dagrocorat
- Fosdagrocorat
- Mapracorat
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Antagonists |
- 7α-Hydroxy-DHEA
- 17α-Methylprogesterone
- Aglepristone
- Asoprisnil
- Asoprisnil ecamate
- C108297
- C113176
- CORT-108297
- Cyproterone acetate
- Exicorilant (CORT-125281)
- Guggulsterone
- Ketoconazole
- Lilopristone
- LLY-2707
- Metapristone (RU-42633)
- Miconazole
- Mifepristone (RU-486)
- Miricorilant (CORT-118335)
- Onapristone
- ORG-34116
- ORG-34517 (SCH-900636)
- ORG-34850
- Pregnenolone 16α-carbonitrile
- Relacorilant (CORT-125134)
- RTI 3021–012
- RTI 3021–022
- Telapristone
- Tibolone
- Toripristone
- Ulipristal acetate
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Others |
Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
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- See also
- Receptor/signaling modulators
- Glucocorticoids and antiglucocorticoids
- Mineralocorticoid receptor modulators
- List of corticosteroids
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Categories:
- Diols
- Glucocorticoids
- Pregnanes
- Triketones
- Systemic hormonal preparation stubs
Hidden categories:
- Articles lacking sources from December 2009
- All articles lacking sources
- Template:drugs.com link with non-standard subpage
- Articles with changed CASNo identifier
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