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Triamcinolon Садржај Upotreba Prodajni oblici Nuspojave Reference Spoljašnje veze Мени за навигацију124-94-7WHOAB09XB02AB08AD11BA06BA0531307APRD0042229046Goodman & Gilman's The Pharmacological Basis of TherapeuticsTriamcinolone - Drugs.comTriamcinolone inhalation - Drugs.comAlcon Receives FDA Approval of Triesence Injectable Triamcinolone Suspension for Use in Eye Surgery„Drugs and Treatments - Nasacort AQ Nasl - Patient Handout”Medline PlusMayoClinicуу

ЛековиСтероидиГлукокортикоиди


sintetičkikortikosteroidinjekcijaekcempsorijazaartritisalergijeulcerozni kolitislupussimpatička oftalmijatemporalni arteritisuveitisokularnainflamacijavitrektomijeastmatičnihacetoniddiacetatTriamcinolon acetonidprednizonaalergijske reakcijeMENDanatphysdevphormcellnocodcongtumrsysieponproclekA10H1H2H3H5










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Triamcinolon




Из Википедије, слободне енциклопедије






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Triamcinolon (lek sa nizom trgovačkih imena: Kenalog, Aristocort, Nasacort, Tri-Nasal, Azmacort, Trilone, Volon A, Tristoject, Fougera, Tricortone,Triesence) je sintetički kortikosteroid koji se može daviti oralno, putem injekcija, inhalaciono, ili topikalno upotrebom ulja ili krema.




Садржај





  • 1 Upotreba


  • 2 Prodajni oblici


  • 3 Nuspojave


  • 4 Reference


  • 5 Spoljašnje veze




Upotreba


Triamcinolon se koristi za nekoliko različitih oboljenja, kao što su ekcem, psorijaza, artritis, alergije, ulcerozni kolitis, lupus, simpatička oftalmija, temporalni arteritis, uveitis, i okularna inflamacija, vizuelizacija u toku vitrektomije, i u prevenciji astmatičnih napada.[1] On ne može pomoći kod astmatičnog napada koji je već počeo.
[2][3][4]



Prodajni oblici


Različite soli triamcinolona su dostupne, uključujući acetonid, benetonid, furetonid, heksacetonid i diacetat.


Triamcinolon acetonid je potentniji tip triamcinolona. On je oko 8 puta efektivniji od prednizona.



Nuspojave


Nuspojave triamcinolona uključuju upalu grla, krvarenje nosa, pojačano kašljanje, glavobolju, i curenje nosa. Bele mrlje u grlu i nosu indiciraju ozbiljne nuzpojave. Simptomi alergijske reakcije su osip, svrab, podnadulost, jaka nesvestica, i problemi disanja. [5]


Dodatna nuspojava kod žena je produženi menstrualni ciklus.



Reference




  1. ^ Keith Parker; Laurence Brunton; Goodman, Louis Sanford; Lazo, John S.; Gilman, Alfred (2006). „Chapter 59. Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs; Inhibitors of the synthesis and actions of adrenocortical hormones”. Goodman & Gilman's The Pharmacological Basis of Therapeutics (11. изд.). New York: McGraw-Hill. ISBN 0071422803. 


  2. ^ Triamcinolone - Drugs.com


  3. ^ Triamcinolone inhalation - Drugs.com


  4. ^ Alcon Receives FDA Approval of Triesence Injectable Triamcinolone Suspension for Use in Eye Surgery


  5. ^ „Drugs and Treatments - Nasacort AQ Nasl - Patient Handout”. WebMD. 



Spoljašnje veze



  • Medline Plus

  • MayoClinic


Triamcinolon
Triamcinolone.svg
Triamcinolone ball-and-stick animation.gif

IUPAC ime
(11β,16α)-9-fluoro-11,16,17,21-tetrahydroxypregna
-1,4-diene-3,20-dione
Klinički podaci
Kategorija trudnoće


  • AU: A


  • US: C (Mogući rizik)


Način primeneOralno, topikalno, IM, intra-artikularno, intra-sinovijalno
Pravni status
Pravni status


  • UK: POM (Samo na recepat)


  • US: Rx-samo



Farmakokinetički podaci
Vezivanje proteina68%
MetabolizamHepatički
Poluvreme eliminacije88 minuta
IzlučivanjeFekalno i renalno

Identifikatori
CAS broj
124-94-7 ДаY
ATC kod
A01AC01 (WHO) D07AB09, D07XB02, H02AB08, R01AD11, R03BA06, S01BA05
PubChemCID 31307
DrugBankAPRD00422
ChemSpider29046
Sinonimi

Click show to see


(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one

Hemijski podaci
Formula
C21H27FO6
Molarna masa394.434 g/mol





































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