Fluperolon acetat Садржај Osobine Reference Literatura Spoljašnje veze Мени за навигацијуacetate.html Monografija2119-75-7WHO66257„Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”10.1021/jp980230o„Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”1174957310.1021/ci000392t„Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”1102028610.1021/jm000942eGoodman & Gilman's The Pharmacological Basis of Therapeutics10.1036/0071422803Foye's Principles of Medicinal ChemistryFluperolon acetatVikimedijinoj ostaviFluperolone acetateу
АлкохолиКарбоксилатни естриЕтриГлукокортикоидиСтероидиКетониОрганофлуориди
organsko jedinjenjeatomaugljenikamolekulsku masuDaMENDanatphysdevphormcellnocodcongtumrsysieponproclekA10H1H2H3H5
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Fluperolon acetat
Иди на навигацију
Иди на претрагу
 | |
| Klinički podaci | |
|---|---|
| Drugs.com | acetate.html Monografija |
| Identifikatori | |
| CAS broj | 2119-75-7  Y |
| ATC kod | D07AB05 (WHO) |
| PubChem | CID 66257 |
| Sinonimi | [(2S)-1-[(8S,9S,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-1-oxo-propan-2-yl] acetate |
| Hemijski podaci | |
| Formula | C24H31FO6 |
| Molarna masa | 434,498 |
SMILES
| |
InChI
| |
Fluperolon acetat je organsko jedinjenje, koje sadrži 24 atoma ugljenika i ima molekulsku masu od 434,498 Da.
Садржај
1 Osobine
2 Reference
3 Literatura
4 Spoljašnje veze
Osobine
| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 6 |
| Broj donora vodonika | 2 |
| Broj rotacionih veza | 4 |
Particioni koeficijent[1] (ALogP) | 2,3 |
Rastvorljivost[2] (logS, log(mol/L)) | -4,7 |
Polarna površina[3] (PSA, Å2) | 100,9 |
Reference
^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
.mw-parser-output .refbeginfont-size:90%;margin-bottom:0.5em.mw-parser-output .refbegin-hanging-indents>ullist-style-type:none;margin-left:0.mw-parser-output .refbegin-hanging-indents>ul>li,.mw-parser-output .refbegin-hanging-indents>dl>ddmargin-left:0;padding-left:3.2em;text-indent:-3.2em;list-style:none.mw-parser-output .refbegin-100font-size:100%
Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
Spoljašnje veze
 | Fluperolon acetat na Vikimedijinoj ostavi. |
- Fluperolone acetate
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
Категорије:
- Алкохоли
- Карбоксилатни естри
- Етри
- Глукокортикоиди
- Стероиди
- Кетони
- Органофлуориди
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