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Pregnan Pregnani Reference Spoljašnje veze Мени за навигацију24909-91-9Interactive imagePregnane6857422„PubChem as a public resource for drug discovery.”2097051910.1016/j.drudis.2010.10.003уреди10.1016/S1574-1400(08)00012-110.1021/jo960108q10.1530/acta.0.021024510.1016/0022-4731(81)90361-7PubChemDiagram na qmul.ac.ukDefinicija pregnanaProgesteron hemijaProgesteron rekord u Evropskoj Bioinformatičkoj bazi podatakHemijska knjigaу

ПрегнаниНеуростероидиПрогестерони


progesteronaugljeno hidratnasteroidaprogesteronaketonaurinumetaboličkijedinjenjasteroidnipregnenipregnadienipregnatrienidvostruku vezukortizonhidrokortizonprogesterondvostruke vezeciproterondanazolfluocinonidMENDanatphysdevphormcellnocodcongtumrsysieponproclekA10H1H2H3H5










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Pregnan




Из Википедије, слободне енциклопедије

(преусмерено са Pregnadientriol)





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Pregnan

Pregnane.svg
Nazivi

IUPAC naziv
(8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene

Identifikacija

CAS broj


  • 24909-91-9


3D model (Jmol)


  • Interactive image


MeSH

Pregnane


PubChem[1][2]CID


  • 6857422



Svojstva

Hemijska formula

C21H36

Molarna masa
288.511 g/mol

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).


Reference infokutije


Pregnan je, indirektno, roditelj progesterona. To je ugljeno hidratna osnova dve serije steroida zasnovane na 5α-pregnanu (originalno alopregnan) i 5β-pregnan (17β-etiletiokolane).


5β-Pregnan je roditelj progesterona, pregnan alkohola, ketona[3], i nekoliko adrenokortikoidni hormona. On se nalazi uglavnom u urinu kao metabolički proizvod jedinjenja 5β-pregnana.[4][5]



Pregnani





Steroid nomenklatura: Pregnani imaju ugljenike 1 do 21.


Pregnani su steroidni derivati sa ugljenicima prisutnim na pozicijama 1 do 21.


Većina biološki signifikantnih pregnan derivata pripada jednoj od dve grupe: pregneni i pregnadieni[6]. Postoji i treća manja klasa pregnatrieni. Pregneni sadrže dvostruku vezu, na primer: kortizon, hidrokortizon, i progesteron. Pregnadieni imaju dve dvostruke veze, na primer: ciproteron, danazol, i fluocinonid.



Reference




  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди


  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 


  3. ^ Nicoletti D, Ghini AA, Burton G (1996). „Oxidative Cyclization of Iodo Ketones. Synthesis of 6-Oxa-5α-pregnane-3,20-dione”. J Org Chem. 61 (19): 6673—6677. doi:10.1021/jo960108q. 


  4. ^ Davis ME, Plotz EJ (1956). „The excretion of neutral steroids in the urine of normal non-pregnant and pregnant women”. Acta Endocrinologica. 21 (3): 245—258. doi:10.1530/acta.0.0210245. 


  5. ^ Beguea R, Morinierea M, Nivoisa C, Sandre D, Padieu P (1981). „Identification of 5β-pregnane-3α,6α,20α-triol in urine of normal newborn infant”. Journal of Steroid Biochemistry. 14 (5): 489—491. doi:10.1016/0022-4731(81)90361-7. 


  6. ^ Beyler R, Hoffman F, Sarett L (1959). „Synthesis of 1,4-Pregnadiene-17α,20α,21-triol-3,11-dione”. J Org Chem. 29 (9): 1386—1387. 



Spoljašnje veze



  • PubChem

  • Diagram na qmul.ac.uk

  • Definicija pregnana

  • Progesteron hemija

  • Progesteron rekord u Evropskoj Bioinformatičkoj bazi podatak

  • Hemijska knjiga










Преузето из „https://sr.wikipedia.org/w/index.php?title=Pregnan&oldid=21481219”










Мени за навигацију


























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Кастелфранко ди Сопра Становништво Референце Спољашње везе Мени за навигацију43°37′18″ СГШ; 11°33′32″ ИГД / 43.62156° СГШ; 11.55885° ИГД / 43.62156; 11.5588543°37′18″ СГШ; 11°33′32″ ИГД / 43.62156° СГШ; 11.55885° ИГД / 43.62156; 11.558853179688„The GeoNames geographical database”„Istituto Nazionale di Statistica”проширитиууWorldCat156923403n850174324558639-1cb14643287r(подаци)

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