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MPPF Vidi još Reference Spoljašnje veze Мени за навигацију155204-26-5Interactive image6603915verifikuj„PubChem as a public resource for drug discovery.”2097051910.1016/j.drudis.2010.10.003уреди10.1016/S1574-1400(08)00012-110.1016/S0969-8051(97)00229-116330560у

Фенолни етриПиперазиниОрганофлуоридиБензамиди


serotoninski 1A receptorfluorom-18radioligandpozitronsku emisionu tomografijumozgu










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MPPF




Из Википедије, слободне енциклопедије






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MPPF

MPPF.png
Nazivi

IUPAC naziv
4-Fluoro-N-[2-[4-(2-metoksifenil)-1-piperazinil]etil]-N-(2-piridil)benzamid

Identifikacija

CAS broj


  • 155204-26-5


3D model (Jmol)


  • Interactive image



PubChem[1][2]CID


  • 6603915



Svojstva

Hemijska formula

C25H27FN4O2

Molarna masa
434,51 g/mol

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).


ДаY verifikuj (šta je ДаYНеН ?)

Reference infokutije


MPPF (2'-metoksifenil-(N-2'-piridinil)-p-fluoro-benzamidoetilipiperazin) je jedinjenje koje se vezuje za serotoninski 1A receptor. Obeležen sa fluorom-18 on je korišten kao radioligand za pozitronsku emisionu tomografiju.[3]
On je između ostalog bio korišten za ispitivanje razlika vezivanja za neuroreceptore u ljudskom mozgu kod osoba različitog pola i uzrasta.[4]



Vidi još


  • WAY-100,635


Reference




  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди


  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 


  3. ^ D. Le Bars (1998). „High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635”. Nuclear Medicine and Biology. 25 (4): 343–350. doi:10.1016/S0969-8051(97)00229-1. 


  4. ^ Nicolas Costes; Merlet, I; Ostrowsky, K; Faillenot, I; Lavenne, F; Zimmer, L; Ryvlin, P; Le Bars, D (2005). „A18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging”. the Journal of Nuclear Medicine. 46 (12): 1980–1989. PMID 16330560. 




Spoljašnje veze











Преузето из „https://sr.wikipedia.org/w/index.php?title=MPPF&oldid=15591905”










Мени за навигацију


























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