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Mosapramin Reference Vidi još Spoljašnje veze Мени за навигацијуИнтернационално име лека89419-40-9WHO425704UZQ7O9SJD0823510.1016/0893-133X(94)00064-7уууу

Атипични антипсихотициДибензазепиниЛактамиХлороарениПиперидиниСпиро једињења


atipični antipsihotikJapanudopaminski antagonistD2D3D4receptore5-HT2 receptoreAzaperonBenperidolBromperidolDroperidolFluanizonHaloperidolLenperonMoperonPipamperonSpiperonTimiperonTrifluperidolKlopimozidFluspirilenPenfluridolPimozidAcepromazinAcetofenazinButaperazinKarfenazinHloracizinHlorproetazinHlorpromazinCijamemazinDiksirazinFluacizinFlufenazinLevomepromazin/MetotrimeprazinMezoridazinPerazinPericijazinPerfenazinPiperacetazinPipotiazinProhlorperazinPromazinPrometazinPropiomazinSulforidazinTietilperazinTiopropazatTioproperazinTioridazinTrifluoperazinTriflupromazinHlorprotiksenKlopentiksolFlupentiksolTiotiksenZuklopentiksolButaklamolFluotracenLoksapinTrimipraminCinuperonMelperonSetoperonIloperidonOkaperidonPaliperidonRisperidonLurasidonePerospironRevospironTiospironZiprasidonAmperozidAripiprazolBifeprunoksBrekspiprazolElopiprazolUmespironAmoksapinAsenapinKarpipraminKlocapraminKlorotepinKlotiapinKlozapinFluperlapinGevotrolinMetitepinMosapraminNDMCOlanzapinPihindonKvetijapinTenilapinZotepinWHO-EMPovučeniKlinička ispitivanjaFaza IIINije dospeo do faze IIIMPSOPSImeprdsrdodbpasspecspvoprocN5A5B5C6A6B6D










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Mosapramin




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Mosapramin
Mosapramine.png

IUPAC ime
1'-[3-(3-hloro-10,11-dihidro-5H-dibenzo[b,f]azepin-5-il)propil]hexahidro-2H-spiro[imidazo[1,2-a]piridin-3,4'-piperidin]-2-on
Klinički podaci
Drugs.comИнтернационално име лека
Način primeneOralno
Pravni status
Pravni status

  • ℞ (Prescription only)

Identifikatori
CAS broj
89419-40-9 ДаY
ATC kod
N05AX10 (WHO)
PubChemCID 4257
UNII
04UZQ7O9SJ ДаY
KEGG
D08235 ДаY
Hemijski podaci
Formula
C28H35ClN4O
Molarna masa479.057 g/mol



Mosapramin (Kremin) je atipični antipsihotik koji se koristi u Japanu.[1] On je potentan dopaminski antagonist sa visokim afinitetom za D2, D3, i D4 receptore,[2] i sa umerenim afinitetom za 5-HT2 receptore.[3]



Reference




  1. ^ Takahashi N, Terao T, Oga T, Okada M. Comparison of risperidone and mosapramine addition to neuroleptic treatment in chronic schizophrenia. Neuropsychobiology. 1999;39(2):81-5. PMID 10072664


  2. ^ Futamura T, Ohashi Y, Yano K, Takahashi Y, Haga K, Fukuda T. The affinities of mosapramine for the dopamine receptor subtypes in human cell lines expressing D2, D3 and D4 receptors. Nippon Yakurigaku Zasshi. (Japanese) 1996 May;107(5):247-53. PMID 8690306


  3. ^ Sumiyoshi T, Suzuki K, Sakamoto H, Yamaguchi N, Mori H, Shiba K, Yokogawa K. Atypicality of several antipsychotics on the basis of in vivo dopamine-D2 and serotonin-5HT2 receptor occupancy. Neuropsychopharmacology. 1995 Feb;12(1):57-64. doi:10.1016/0893-133X(94)00064-7 PMID 7766287



Vidi još


  • Karpipramin

  • Klokapramin


Spoljašnje veze










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