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Zotepin Садржај Farmakologija Reference Literatura Spoljašnje veze Мени за навигацијуInternacionalno ime leka26615-21-4WHO5736103none5534U29O83JAZWD01321CHEBI:32316CHEMBL285802Goodman & Gilman's The Pharmacological Basis of Therapeutics10.1036/0071422803PDR: Physicians Desk Reference 2010 (Physicians' Desk Reference (Pdr))Losizopin sugar-coated tablets & fine granulesуууууу

Атипични антипсихотициДибензотиепиниХлороарениЕтри


atipični antipsihotikšizofrenijeNemačkoj1990Japanu1982antagonistnogdopaminskeserotoninske receptoreafinitetD1D2 receptore5-HT2A5-HT2C5-HT65-HT7 receptoreinhibitor norepinefrinskog preuzimanjaAzaperonBenperidolBromperidolDroperidolFluanizonHaloperidolLenperonMoperonPipamperonSpiperonTimiperonTrifluperidolKlopimozidFluspirilenPenfluridolPimozidAcepromazinAcetofenazinButaperazinKarfenazinHloracizinHlorproetazinHlorpromazinCijamemazinDiksirazinFluacizinFlufenazinLevomepromazin/MetotrimeprazinMezoridazinPerazinPericijazinPerfenazinPiperacetazinPipotiazinProhlorperazinPromazinPrometazinPropiomazinSulforidazinTietilperazinTiopropazatTioproperazinTioridazinTrifluoperazinTriflupromazinHlorprotiksenKlopentiksolFlupentiksolTiotiksenZuklopentiksolButaklamolFluotracenLoksapinTrimipraminCinuperonMelperonSetoperonIloperidonOkaperidonPaliperidonRisperidonLurasidonePerospironRevospironTiospironZiprasidonAmperozidAripiprazolBifeprunoksBrekspiprazolElopiprazolUmespironAmoksapinAsenapinKarpipraminKlocapraminKlorotepinKlotiapinKlozapinFluperlapinGevotrolinMetitepinMosapraminNDMCOlanzapinPihindonKvetijapinTenilapinZotepinWHO-EMPovučeniKlinička ispitivanjaFaza IIINije dospeo do faze IIIMPSOPSImeprdsrdodbpasspecspvoprocN5A5B5C6A6B6DAkrivastinAlinastinAstemizolAzelastinBamirastinBarmastinBepiastinBepotastinBilastinKabastinenKarebastinKetirizinKlemastinKlemizolKlobenztropinDorastinEbastinEmedastinEpinastinFlezelastinKetotifenLatrepirdinLevokabastinLinetastinLoratadinMapinastinMebhidrolinMizolastinMoksastinNoberastinOktastinOlopatadinPerastinPiklopastinRokastinRupatadinSetastinTalastinTemelastinTerfenadinZepastinDesloratadinFeksofenadinCetirizin‎‎LevocetirizinBelarizinEfletirizinElbanizinFlotrenizinMedrilaminNapaktadinPibaksizinTagorizinTrelnarizinTrenizinVapitadin










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Zotepin




Из Википедије, слободне енциклопедије






Иди на навигацију
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Zotepin
Zotepine structure.png

IUPAC ime
2-[(8-​hlorodibenzo(b,f)​tiepin-​10-​il)oksi]-​N,N-​dimetiletanamin
Klinički podaci
Drugs.comInternacionalno ime leka
Način primeneOralno
Pravni status
Pravni status

  • Nije kontrolisana supstanca, Rx Only.

Identifikatori
CAS broj
26615-21-4 ДаY
ATC kod
N05AX11 (WHO)
PubChemCID 5736
IUPHAR/BPS103
DrugBank
none ДаY
ChemSpider
5534 ДаY
UNII
U29O83JAZW ДаY
KEGG
D01321 ДаY
ChEBI
CHEBI:32316 ДаY
ChEMBL
CHEMBL285802 ДаY
Hemijski podaci
Formula
C18H18ClNOS
Molarna masa331,86



Zotepin (Nipolept, Losizopilon, Lodopin, Setous) je atipični antipsihotik koji se koristi za tretiranje akutne i hronične šizofrenije. On je u upotrebi u Nemačkoj od 1990. i Japanu od 1982. Zotepin nije odobren za upotrebu u Sjedinjenim Državama.




Садржај





  • 1 Farmakologija


  • 2 Reference


  • 3 Literatura


  • 4 Spoljašnje veze




Farmakologija


Antipsihotičko dejstvo zotepina je posredovano putem njegovog antagonistnog dejstva na dopaminske i serotoninske receptore. Zotepin ima visok afinitet za D1 i D2 receptore. On takođe utiče na 5-HT2A, 5-HT2C, 5-HT6, i 5-HT7 receptore. Osim toga on je inhibitor norepinefrinskog preuzimanja, što verovatno doprinosi njegovoj efikasnosti protiv negativnih simptoma šizofrenije.[1][2]



Reference




  1. ^ Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803. 


  2. ^ Pdr Staff (2009). PDR: Physicians Desk Reference 2010 (Physicians' Desk Reference (Pdr)). Rozelle, N.S.W: Thomson Reuters. ISBN 1-56363-748-0. 



Literatura



Spoljašnje veze




  • Losizopin sugar-coated tablets & fine granules[мртва веза] (PDF)









Star of life.svgMolimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).








Преузето из „https://sr.wikipedia.org/w/index.php?title=Zotepin&oldid=20764334”










Мени за навигацију



























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