Skip to main content

Zotepin Садржај Farmakologija Reference Literatura Spoljašnje veze Мени за навигацијуInternacionalno ime leka26615-21-4WHO5736103none5534U29O83JAZWD01321CHEBI:32316CHEMBL285802Goodman & Gilman's The Pharmacological Basis of Therapeutics10.1036/0071422803PDR: Physicians Desk Reference 2010 (Physicians' Desk Reference (Pdr))Losizopin sugar-coated tablets & fine granulesуууууу

Атипични антипсихотициДибензотиепиниХлороарениЕтри


atipični antipsihotikšizofrenijeNemačkoj1990Japanu1982antagonistnogdopaminskeserotoninske receptoreafinitetD1D2 receptore5-HT2A5-HT2C5-HT65-HT7 receptoreinhibitor norepinefrinskog preuzimanjaAzaperonBenperidolBromperidolDroperidolFluanizonHaloperidolLenperonMoperonPipamperonSpiperonTimiperonTrifluperidolKlopimozidFluspirilenPenfluridolPimozidAcepromazinAcetofenazinButaperazinKarfenazinHloracizinHlorproetazinHlorpromazinCijamemazinDiksirazinFluacizinFlufenazinLevomepromazin/MetotrimeprazinMezoridazinPerazinPericijazinPerfenazinPiperacetazinPipotiazinProhlorperazinPromazinPrometazinPropiomazinSulforidazinTietilperazinTiopropazatTioproperazinTioridazinTrifluoperazinTriflupromazinHlorprotiksenKlopentiksolFlupentiksolTiotiksenZuklopentiksolButaklamolFluotracenLoksapinTrimipraminCinuperonMelperonSetoperonIloperidonOkaperidonPaliperidonRisperidonLurasidonePerospironRevospironTiospironZiprasidonAmperozidAripiprazolBifeprunoksBrekspiprazolElopiprazolUmespironAmoksapinAsenapinKarpipraminKlocapraminKlorotepinKlotiapinKlozapinFluperlapinGevotrolinMetitepinMosapraminNDMCOlanzapinPihindonKvetijapinTenilapinZotepinWHO-EMPovučeniKlinička ispitivanjaFaza IIINije dospeo do faze IIIMPSOPSImeprdsrdodbpasspecspvoprocN5A5B5C6A6B6DAkrivastinAlinastinAstemizolAzelastinBamirastinBarmastinBepiastinBepotastinBilastinKabastinenKarebastinKetirizinKlemastinKlemizolKlobenztropinDorastinEbastinEmedastinEpinastinFlezelastinKetotifenLatrepirdinLevokabastinLinetastinLoratadinMapinastinMebhidrolinMizolastinMoksastinNoberastinOktastinOlopatadinPerastinPiklopastinRokastinRupatadinSetastinTalastinTemelastinTerfenadinZepastinDesloratadinFeksofenadinCetirizin‎‎LevocetirizinBelarizinEfletirizinElbanizinFlotrenizinMedrilaminNapaktadinPibaksizinTagorizinTrelnarizinTrenizinVapitadin










(function()var node=document.getElementById("mw-dismissablenotice-anonplace");if(node)node.outerHTML="u003Cdiv class="mw-dismissable-notice"u003Eu003Cdiv class="mw-dismissable-notice-close"u003E[u003Ca tabindex="0" role="button"u003Eсакријu003C/au003E]u003C/divu003Eu003Cdiv class="mw-dismissable-notice-body"u003Eu003Cdiv id="localNotice" lang="sr" dir="ltr"u003Eu003Cdiv class="noticebanner"u003Eu003Cdiv class="plainlinks" style="background-image: -moz-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -o-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -webkit-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: linear-gradient(to bottom, #fefefe, #fefefe, #f0f0f0);; -moz-border-radius: 10px; -webkit-border-radius: 10px; border-radius:10px; margin-top:10px; position:relative; height:25px; border-style:solid; border-width:1px; color:#aaa; border-color:u0026#32;; border:; font-family: u0026#39;Helveticau0026#39;, u0026#39;Arialu0026#39;, sans-serif; line-height: 18px; background-color:; overflow:hidden;"u003Eu003Cdiv style="display:block; position: absolute; top:4px; width:100%; text-align:center;;"u003Eu003Cdiv style="font-weight:bold; color:#000085; font-size:14px; line-height:25px"u003Eu003Cdiv style="padding-left:50px;"u003Eu003C/divu003Eu003C/divu003Eu003Cdiv style="margin-top: 2px; font-weight:normal; color:#555; font-size:15px; line-height:15px;"u003Eu003Cdiv style="padding-left:50px;"u003EУчествуј у u003Cbu003Eu003Ca href="https://meta.wikimedia.org/wiki/%D0%92%D0%B5%D0%BB%D0%B8%D0%BA%D0%BE_%D0%BF%D1%80%D0%BE%D0%BB%D0%B5%D1%9B%D0%BD%D0%BE_%D1%81%D1%80%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%9A%D0%B5_%D0%9E%D1%81%D1%82%D0%B0%D0%B2%D0%B5" class="extiw" title="meta:Велико пролећно сређивање Оставе"u003EВеликом пролећном сређивању Оставеu003C/au003Eu003C/bu003E од 15. марта до 15. априла!u003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Enu003Cdiv class="noticebanner"u003Eu003Cdiv class="plainlinks" style="background-image: -moz-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -o-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -webkit-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: linear-gradient(to bottom, #fefefe, #fefefe, #f0f0f0);; -moz-border-radius: 10px; -webkit-border-radius: 10px; border-radius:10px; margin-top:10px; position:relative; height:25px; border-style:solid; border-width:1px; color:#aaa; border-color:u0026#32;; border:; font-family: u0026#39;Helveticau0026#39;, u0026#39;Arialu0026#39;, sans-serif; line-height: 18px; background-color:; overflow:hidden;"u003Eu003Cdiv style="display:block; position: absolute; top:4px; width:100%; text-align:center;;"u003Eu003Cdiv style="font-weight:bold; color:#000085; font-size:14px; line-height:25px"u003Eu003Cdiv style="padding-left:50px;"u003Eu003C/divu003Eu003C/divu003Eu003Cdiv style="margin-top: 2px; font-weight:normal; color:#555; font-size:15px; line-height:15px;"u003Eu003Cdiv style="padding-left:50px;"u003EТакмичи се у писању u003Cbu003Eu003Ca href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A2%D0%B0%D0%BA%D0%BC%D0%B8%D1%87%D0%B5%D1%9A%D0%B5_%D1%83_%D0%BF%D0%B8%D1%81%D0%B0%D1%9A%D1%83_%D1%87%D0%BB%D0%B0%D0%BD%D0%B0%D0%BA%D0%B0/%D0%A6%D0%95%D0%95_%D0%BF%D1%80%D0%BE%D0%BB%D0%B5%D1%9B%D0%B5_2019" title="Википедија:Такмичење у писању чланака/ЦЕЕ пролеће 2019"u003Eчланака о средњој и источној Европиu003C/au003Eu003C/bu003E од 21. марта до 31. маја!u003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Enu003Cdiv class="noticebanner"u003Eu003Cdiv class="plainlinks" style="background-image: -moz-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -o-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -webkit-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: linear-gradient(to bottom, #fefefe, #fefefe, #f0f0f0);; -moz-border-radius: 10px; -webkit-border-radius: 10px; border-radius:10px; margin-top:10px; position:relative; height:25px; border-style:solid; border-width:1px; color:#aaa; border-color:u0026#32;; border:; font-family: u0026#39;Helveticau0026#39;, u0026#39;Arialu0026#39;, sans-serif; line-height: 18px; background-color:; overflow:hidden;"u003Eu003Cdiv style="display:block; position: absolute; top:4px; width:100%; text-align:center;;"u003Eu003Cdiv style="font-weight:bold; color:#000085; font-size:14px; line-height:25px"u003Eu003Cdiv style="padding-left:50px;"u003Eu003C/divu003Eu003C/divu003Eu003Cdiv style="margin-top: 2px; font-weight:normal; color:#555; font-size:15px; line-height:15px;"u003Eu003Cdiv style="padding-left:50px;"u003EУ току су расправе о u003Cbu003Eu003Ca href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%93%D0%BB%D0%B0%D1%81%D0%B0%D1%9A%D0%B5/%D0%9F%D1%80%D0%B5%D0%B4%D0%BB%D0%BE%D0%B3/%D0%A3%D0%B2%D0%BE%D1%92%D0%B5%D1%9A%D0%B5_%D0%BE%D0%BF%D1%88%D1%82%D0%B5_%D0%BF%D1%80%D0%B8%D0%BF%D1%80%D0%B5%D0%BC%D0%B5" title="Википедија:Гласање/Предлог/Увођење опште припреме"u003Eувођењу опште припремеu003C/au003Eu003C/bu003E и u003Cbu003Eu003Ca href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%93%D0%BB%D0%B0%D1%81%D0%B0%D1%9A%D0%B5/%D0%9F%D1%80%D0%B5%D0%B4%D0%BB%D0%BE%D0%B3/%D0%9F%D1%80%D0%B0%D0%B2%D0%BE_%D0%B0%D0%B4%D0%BC%D0%B8%D0%BD%D0%B8%D1%81%D1%82%D1%80%D0%B0%D1%82%D0%BE%D1%80_%D0%B8%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B5%D1%98%D1%81%D0%B0" title="Википедија:Гласање/Предлог/Право администратор интерфејса"u003Eадминистраторима интерфејсаu003C/au003Eu003C/bu003E.u003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Enu003Cdiv class="noticebanner"u003Eu003Cdiv class="plainlinks" style="background-image: -moz-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -o-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: -webkit-linear-gradient(top, #fefefe, #fefefe, #f0f0f0); background-image: linear-gradient(to bottom, #fefefe, #fefefe, #f0f0f0);; -moz-border-radius: 10px; -webkit-border-radius: 10px; border-radius:10px; margin-top:10px; position:relative; height:25px; border-style:solid; border-width:1px; color:#aaa; border-color:u0026#32;; border:; font-family: u0026#39;Helveticau0026#39;, u0026#39;Arialu0026#39;, sans-serif; line-height: 18px; background-color:; overflow:hidden;"u003Eu003Cdiv style="display:block; position: absolute; top:4px; width:100%; text-align:center;;"u003Eu003Cdiv style="font-weight:bold; color:#000085; font-size:14px; line-height:25px"u003Eu003Cdiv style="padding-left:50px;"u003Eu003C/divu003Eu003C/divu003Eu003Cdiv style="margin-top: 2px; font-weight:normal; color:#555; font-size:15px; line-height:15px;"u003Eu003Cdiv style="padding-left:50px;"u003EУ току је гласање о u003Cbu003Eu003Ca href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%93%D0%BB%D0%B0%D1%81%D0%B0%D1%9A%D0%B5/%D0%9F%D0%BE%D0%B2%D0%B5%D1%9B%D0%B0%D1%9A%D0%B5_%D0%BF%D1%80%D0%BE%D1%81%D1%82%D0%BE%D1%80%D0%B0_%D0%B7%D0%B0_%D1%81%D0%BB%D0%B8%D0%BA%D0%B5_%D0%BD%D0%B0_%D0%B3%D0%BB%D0%B0%D0%B2%D0%BD%D0%BE%D1%98_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8" title="Википедија:Гласање/Повећање простора за слике на главној страни"u003Eповећању простора за слике на Главној страниu003C/au003Eu003C/bu003E.u003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003Eu003C/divu003E";());




Zotepin




Из Википедије, слободне енциклопедије






Иди на навигацију
Иди на претрагу

































Zotepin
Zotepine structure.png

IUPAC ime
2-[(8-​hlorodibenzo(b,f)​tiepin-​10-​il)oksi]-​N,N-​dimetiletanamin
Klinički podaci
Drugs.comInternacionalno ime leka
Način primeneOralno
Pravni status
Pravni status

  • Nije kontrolisana supstanca, Rx Only.

Identifikatori
CAS broj
26615-21-4 ДаY
ATC kod
N05AX11 (WHO)
PubChemCID 5736
IUPHAR/BPS103
DrugBank
none ДаY
ChemSpider
5534 ДаY
UNII
U29O83JAZW ДаY
KEGG
D01321 ДаY
ChEBI
CHEBI:32316 ДаY
ChEMBL
CHEMBL285802 ДаY
Hemijski podaci
Formula
C18H18ClNOS
Molarna masa331,86



Zotepin (Nipolept, Losizopilon, Lodopin, Setous) je atipični antipsihotik koji se koristi za tretiranje akutne i hronične šizofrenije. On je u upotrebi u Nemačkoj od 1990. i Japanu od 1982. Zotepin nije odobren za upotrebu u Sjedinjenim Državama.




Садржај





  • 1 Farmakologija


  • 2 Reference


  • 3 Literatura


  • 4 Spoljašnje veze




Farmakologija


Antipsihotičko dejstvo zotepina je posredovano putem njegovog antagonistnog dejstva na dopaminske i serotoninske receptore. Zotepin ima visok afinitet za D1 i D2 receptore. On takođe utiče na 5-HT2A, 5-HT2C, 5-HT6, i 5-HT7 receptore. Osim toga on je inhibitor norepinefrinskog preuzimanja, što verovatno doprinosi njegovoj efikasnosti protiv negativnih simptoma šizofrenije.[1][2]



Reference




  1. ^ Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803. 


  2. ^ Pdr Staff (2009). PDR: Physicians Desk Reference 2010 (Physicians' Desk Reference (Pdr)). Rozelle, N.S.W: Thomson Reuters. ISBN 1-56363-748-0. 



Literatura



Spoljašnje veze




  • Losizopin sugar-coated tablets & fine granules[мртва веза] (PDF)









Star of life.svgMolimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).








Преузето из „https://sr.wikipedia.org/w/index.php?title=Zotepin&oldid=20764334”










Мени за навигацију



























(window.RLQ=window.RLQ||[]).push(function()mw.config.set("wgPageParseReport":"limitreport":"cputime":"1.352","walltime":"1.599","ppvisitednodes":"value":8782,"limit":1000000,"ppgeneratednodes":"value":0,"limit":1500000,"postexpandincludesize":"value":974750,"limit":2097152,"templateargumentsize":"value":110278,"limit":2097152,"expansiondepth":"value":25,"limit":40,"expensivefunctioncount":"value":0,"limit":500,"unstrip-depth":"value":0,"limit":20,"unstrip-size":"value":2824,"limit":5000000,"entityaccesscount":"value":0,"limit":400,"timingprofile":["100.00% 860.583 1 -total"," 30.77% 264.769 1 Шаблон:Drugbox-lat"," 29.46% 253.522 4 Шаблон:Navbox_with_collapsible_sections"," 27.98% 240.804 2 Шаблон:Infobox"," 21.89% 188.372 34 Шаблон:Navbox_subgroup"," 11.67% 100.409 1 Шаблон:Мртва_веза"," 10.88% 93.608 1 Шаблон:Fix"," 10.45% 89.900 1 Шаблон:Reflist"," 9.69% 83.418 1 Шаблон:Holinergici-lat"," 9.42% 81.034 3 Шаблон:Navbox"],"scribunto":"limitreport-timeusage":"value":"0.283","limit":"10.000","limitreport-memusage":"value":6372061,"limit":52428800,"cachereport":"origin":"mw1272","timestamp":"20190410065705","ttl":2592000,"transientcontent":false););"@context":"https://schema.org","@type":"Article","name":"Zotepin","url":"https://sr.wikipedia.org/wiki/Zotepin","sameAs":"http://www.wikidata.org/entity/Q226905","mainEntity":"http://www.wikidata.org/entity/Q226905","author":"@type":"Organization","name":"u0421u0430u0440u0430u0434u043du0438u0446u0438 u043fu0440u043eu0458u0435u043au0430u0442u0430 u0412u0438u043au0438u043cu0435u0434u0438u0458u0435","publisher":"@type":"Organization","name":"Wikimedia Foundation, Inc.","logo":"@type":"ImageObject","url":"https://www.wikimedia.org/static/images/wmf-hor-googpub.png","datePublished":"2012-12-26T00:45:44Z","dateModified":"2018-08-25T21:50:21Z","image":"https://upload.wikimedia.org/wikipedia/commons/d/d4/Zotepine_structure.png"(window.RLQ=window.RLQ||[]).push(function()mw.config.set("wgBackendResponseTime":147,"wgHostname":"mw1262"););
-

Popular posts from this blog

Sahara Skak | Bilen | Luke uk diar | NawigatsjuunCommonskategorii: SaharaWikivoyage raisfeerer: Sahara26° N, 13° O

Image
Öömrang ArtiikelAfrikooKliimatologii wüüsteerdUSASchiisklunafrikooAtlantikRuad SiaSaheldüneroaseLibyenTuneesienDünerbergerAlpen (function()var node=document.getElementById("mw-dismissablenotice-anonplace");if(node)node.outerHTML="u003Cdiv class="mw-dismissable-notice"u003Eu003Cdiv class="mw-dismissable-notice-close"u003E[u003Ca tabindex="0" role="button"u003EFersteegu003C/au003E]u003C/divu003Eu003Cdiv class="mw-dismissable-notice-body"u003Eu003Cdiv id="localNotice" lang="frr" dir="ltr"u003Eu003Cdiv id="sitenotice"u003Enu003Ccenteru003Enu003Ctable class="rahmenfarbe4" style="border-style: solid; border-width: thin; width: 70%;"u003Ennu003Ctbodyu003Eu003Ctru003Enu003Ctd style="text-align:center;"u003Eu003Ca href="/wiki/Datei:Nordfriesischeflagge.svg" class="image"u003Eu003Cimg alt="Nordfriesischeflagge.svg" src="//...
Read more

The fall designs the understood secretary. Looking glass Science Shock Discovery Hot Everybody Loves Raymond Smile 곳 서비스 성실하다 Defas Kaloolon Definition: To combine or impregnate with sulphur or any of its compounds as to sulphurize caoutchouc in vulcanizing Flame colored Reason Useful Thin Help 갖다 유명하다 낙엽 장례식 Country Iron Definition: A fencer a gladiator one who exhibits his skill in the use of the sword Definition: The American black throated bunting Spiza Americana Nostalgic Needy Method to my madness 시키다 평가되다 전부 소설가 우아하다 Argument Tin Feeling Representative Gym Music Gaur Chicken 일쑤 코치 편 학생증 The harbor values the sugar. Vasagle Yammoe Enstatite Definition: Capable of being limited Road Neighborly Five Refer Built Kangaroo 비비다 Degree Release Bargain Horse 하루 형님 유교 석 동부 괴롭히다 경제력

Image
The fall designs the understood secretary. Looking glass Science Shock Discovery Hot Everybody Loves Raymond Smile 곳 서비스 성실하다 Defas Kaloolon Definition: To combine or impregnate with sulphur or any of its compounds as to sulphurize caoutchouc in vulcanizing Flame colored Reason Useful Thin Help 갖다 유명하다 낙엽 장례식 Country Iron Definition: A fencer a gladiator one who exhibits his skill in the use of the sword Definition: The American black throated bunting Spiza Americana Nostalgic Needy Method to my madness 시키다 평가되다 전부 소설가 우아하다 Argument Tin Feeling Representative Gym Music Gaur Chicken 일쑤 코치 편 학생증 The harbor values the sugar. Vasagle Yammoe Enstatite Definition: Capable of being limited Road Nei...
Read more

19. јануар Садржај Догађаји Рођења Смрти Празници и дани сећања Види још Референце Мени за навигацијуу

Image
1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30.31.1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30.31.1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30.31.1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30.31.1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30.1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30. ЈануарДани деветнаестиГрегоријанском календарупреступним годинама (function()var node=document.getElementById("mw-dismissabl...
Read more