Nafadotrid Reference Spoljašnje veze Мени за навигацију149649-22-9Interactive image44Nafadotride3408722verifikuj„PubChem as a public resource for drug discovery.”2097051910.1016/j.drudis.2010.10.003уреди10.1016/S1574-1400(08)00012-1у
Допамински антагонистиПиролидиниАмидиНитридиНафтолни етри
dopaminski antagonistD3
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Nafadotrid
Иди на навигацију
Иди на претрагу
 | |
| Nazivi | |
|---|---|
IUPAC naziv N[(2S)-1-butilpirolidin-2-il]metil4-cijano-1-metoksi-2-naftamid | |
| Identifikacija | |
CAS broj |
|
3D model (Jmol) |
|
IUPHAR/BPS |
|
MeSH | Nafadotride |
PubChem[1][2]CID |
|
SMILES
| |
| Svojstva | |
Hemijska formula | C22H27N3O2 |
Molarna masa | 365,48 g·mol−1 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
 Y verifikuj (šta je  Y Н ?) | |
Reference infokutije | |
Nafadotrid je dopaminski antagonist se relativno dobrom selektivnošću za D3 podtip (9.6 puta je seleltivniji za D3 nego D2).[3]
Reference
^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.
Spoljašnje veze
Категорије:
- Допамински антагонисти
- Пиролидини
- Амиди
- Нитриди
- Нафтолни етри
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